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RAC1 — TYR

Text-mined interactions from Literome

Debidda et al., J Biol Chem 2005 (Inflammation) : We also found that although active RhoA, Rac1 , and Cdc42 could all mediate Ser-727 and Tyr-705 phosphorylation and nuclear translocation of STAT3, the Rho GTPases were able to induce STAT3 activation independently of the interleukin-6 autocrine pathway, and active RhoA, Rac1, or Cdc42 could not form a stable complex with STAT3 as previously suggested, indicating an unappreciated mechanism of STAT3 activation by the Rho GTPases
Liu et al., J Biol Chem 2006 : Induction of STAT3 Tyr705 and Ser727 phosphorylations by Galpha ( s ) QL was suppressed by inhibition of protein kinase A, Janus kinase 2/3, Rac1 , c-Jun N-terminal kinase (JNK), or phosphatidylinositol 3-kinase, and a similar profile was observed in response to beta2-adrenergic receptor stimulation
Huang et al., J Biol Chem 2011 : Here, we show that ARV induced phosphorylation of caveolin-1 ( Tyr ( 14 ) ), dynamin-2 expression, and Rac1 activation through activation of p38 MAPK and Src in the early stage of the virus life cycle is beneficial for virus entry and productive infection