Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MIP

Text-mined interactions from Literome

Kurosaka et al., Biochem Biophys Res Commun 2003 (MAP Kinase Signaling System) : We then examined whether or not ERK activation is involved in the production of MIP-2 by employing selective inhibitors for MAP kinase kinase 1/2, PD98059, and U0126 ... These results suggest that activation of ERK is involved in the production of MIP-2 on coculturing of macrophages with late apoptotic cells
Golestaneh et al., J Biol Chem 2004 (MAP Kinase Signaling System) : Our studies show that ERK1/2 and JNK signaling pathways are required for Mip expression in lens epithelia explants induced to differentiate by FGF-2
Iyoda et al., American journal of physiology. Renal physiology 2010 : Additionally, we observed that IL-17A and IL-17F induced MAPK ( p38 MAPK, ERK1/2, and JNK ) activation and that pharmacological inhibitors of p38 MAPK ( SB203580 ) and ERK1/2 ( U0126 ), but not JNK ( SP600125 ), blocked the IL-17A/IL-17F mediated MCP-1 and MIP-2 release
Yan et al., J Biol Chem 2012 (Inflammation...) : Moreover, both ERK1/2 and p38 MAPK are involved in C/EBP induction and TNF-a, MIP-2, and MIP-1a production induced by IgG IC
Li et al., Chest 2013 (Disease Models, Animal...) : We found that high Vt mechanical ventilation increased microvascular permeability, neutrophil influx, production of free radicals, MIP-2 and TGF-ß1 proteins, positive staining of a-smooth muscle actin and S100A4/fibroblast-specific protein-1, Masson trichrome staining and extracellular collagen, and activation of lumican and ERK1/2 in wild-type mice