◀ Back to EPHB2

EPHB2 — LTB

Text-mined interactions from Literome

Klein et al., Cell Signal 2001 (MAP Kinase Signaling System) : LPS, fMLP, and LTB ( 4 ) stimulated similar levels of ERK and Akt activation
Tong et al., Clin Cancer Res 2002 (Neoplasms, Experimental...) : In contrast, LTB4 stimulated proliferation of these cell lines and induced ERK1/2 phosphorylation ... The growth-stimulatory effect and ERK1/2 phosphorylation induced by LTB4 were inhibited by LY293111
Lee et al., Biochem Biophys Res Commun 2005 : sPLA ( 2 ) -IB also stimulated mitogen activated protein kinase ERK , but its activity was not required for LTB4 production
Tong et al., Biochem Biophys Res Commun 2005 (Pancreatic Neoplasms) : The MEK inhibitors, PD98059 and U0126, blocked LTB4 stimulated ERK1/2 activation and cell proliferation
Profita et al., Allergy 2005 (Pulmonary Disease, Chronic Obstructive) : The results obtained show that muscarinic receptors may be involved in airway inflammation in COPD subjects through ACh induced, ERK1/2 dependent LTB4 release
Sitrin et al., J Immunol 2006 : Pretreating neutrophils with methyl-beta-cyclodextrin, a lipid raft disrupting agent, suppressed intracellular Ca ( 2+ ) mobilization and ERK1/2 phosphorylation in response to LTB4 but had no effect on either of these responses to fMLP
Campos et al., Mol Immunol 2009 : Endogenous LTB ( 4 ) contributed to Fc gammaR mediated activation of PKC-alpha, ERK 1/2 and PI3K, while endogenous cysLTs contributes to activation of PKC-delta, p38 and PI3K