Gene interactions and pathways from curated databases and text-mining

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NFKB1 — PIAS4

Text-mined interactions from Literome

Zhang et al., FEBS Lett 2004 : PIASy represses TRIF induced ISRE and NF-kappaB activation but not apoptosis ... In reporter gene assays, PIASy dramatically inhibits TRIF induced NF-kappaB , ISRE and IFN-beta activation but not TRIF induced apoptosis
Shuai et al., Cell Res 2006 : This article is to review the role of PIAS proteins in the regulation of STAT and NF-kB signaling pathways
Albor et al., J Biol Chem 2006 (Muscular Dystrophies, Limb-Girdle) : Conversely, Piasy inhibited NFkappaB activity under the same conditions and sensitized keratinocytes to apoptosis induced by TNFalpha and UVB
Mabb et al., Nat Cell Biol 2006 : PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress
Albor et al., Mol Carcinog 2007 (Carcinoma, Squamous Cell...) : Piasy inhibits NF-kappaB activity, and promotes keratinocyte apoptosis in response to UV and TNF-alpha