Gene interactions and pathways from curated databases and text-mining

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NCF2 — TNF

Text-mined interactions from Literome

Gauss et al., J Leukoc Biol 2005 : As p67phox can be up-regulated by tumor necrosis factor alpha (TNF-alpha) , which activates AP-1, we hypothesized that TNF-alpha might regulate NCF2transcription via AP-1 ... Thus, we have identified a novel NCF2 promoter/enhancer domain, which is essential for TNF-alpha induced up-regulation of p67phox
Ammons et al., J Biol Chem 2007 : NCF2 , the gene encoding the NADPH oxidase cytosolic component p67(phox), is up-regulated by TNF-alpha , and we recently mapped a region in the NCF2 promoter that was required for this TNF-alpha dependent response ... Knockdown of PLAGL2 protein inhibited up-regulation of NCF2 transcript, p67(phox) protein expression, and subsequent superoxide production in response to TNF-alpha
Gauss et al., J Leukoc Biol 2007 : Pharmacological inhibitors of NF-kappaB activation blocked TNF-alpha induced up-regulation of NCF1, NCF2 , and CYBB message, which correlated with a reduction in expression of the corresponding oxidase proteins and decreased O2*- production
Strieter et al., Science 1989 : Human endothelial cells produced a neutrophil chemotactic factor ( NCF ) upon stimulation with tumor necrosis factor-alpha (TNF-alpha) , interleukin-1 beta (IL-1 beta), or lipopolysaccharide (LPS)