Lopez et al., J Interferon Cytokine Res 2003
:
IFN-gamma ( 100 U/ml ) and TNF-alpha ( 1000 U/ml ) or IL-5 ( 200 pM ) caused a significant increase in the expression of the eosinophil peroxidase (EPO) and the major basic protein (MBP) genes
Kanda et al., J Allergy Clin Immunol 2009
(Bronchial Hyperreactivity...) :
Finally, in vitro and at low concentrations, IFN-gamma increased eosinophil peroxidase release, potentiated chemotaxis, and prolonged survival, suggesting the existence of an autocrine mechanism
Vannucchi et al., Br J Haematol 1994
:
These data indicate that Epo production by hepatoma cells in vitro is inhibited by IFN-gamma , and that a complex network of interacting cytokines may regulate Epo production in response to an hypoxic stimulus