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CCR5 — MDM2

Text-mined interactions from Literome

Atemezem et al., Biochem J 2001 : Therefore both AGP glycans and MDM CCR5 are involved in the binding of AGP to MDM. This suggests that the inhibitory effect of AGP on the infection of human primary macrophages by R5 HIV-1 may be related to specific binding of AGP to a macrophage membrane lectin or lectin-like component and to CCR5
Perez-Bercoff et al., J Virol 2003 : Although MDM activation by immobilized IgG induced high levels of macrophage derived chemokine secretion as well as a sustained down-regulation of CD4 and a transient decrease in CCR5 expression, these factors did not appear to play a major role in the suppression of HIV-1 replication