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ENO1 — MYC
Pathways - manually collected, often from reviews:
-
FastForward regulation:
ENO1
→
MYC
(transcriptional regulation, decrease)
Chaudhary et al., Biochemistry 1995*
Evidence: DNABINDING, PROMACTIVITY
-
FastForward regulation:
ENO1
→
MYC
(transcriptional regulation, unknown)
Ray et al., Mol Cell Biol 1991*
Evidence: DNABINDING, PROMACTIVITY
-
FastForward regulation:
ENO1
→
MYC
(transcriptional regulation, increase)
Hsu et al., Mol Cell Biol 2008
Evidence: DNABINDING, PROMACTIVITY
-
NCI Pathway Database Notch signaling pathway:
ENO1 (ENO1)
→
MYC (MYC)
(transcription, inhibits)
Satoh et al., J Biol Chem 2004*, Weng et al., Genes Dev 2006*, Palomero et al., Proc Natl Acad Sci U S A 2006*, Liao et al., Carcinogenesis 2007*, Hsu et al., Mol Cell Biol 2008
Evidence: mutant phenotype, reporter gene, physical interaction
Text-mined interactions from Literome
Mizukami et al., J Biol Chem 2004
(Anoxia...) :
The induction of
alpha-enolase by ERK1/2 appears to be
mediated by
c-Myc
Liu et al., Proteomics 2012
(Nasopharyngeal Neoplasms) :
Overexpressed
ENO1 not only restored cell proliferation and cell-cycle progression, but also antagonized the regulation of NESG1 to cell-cycle regulators p21 and CCNA1 expression as well as
induced the expression of
C-Myc , pRB, and E2F1 in NESG1 ovexpressed NPC cells
Contino et al., BMC cancer 2013
(Breast Neoplasms...) :
MBP-1 is a transcriptional
repressor of the
c-MYC gene that acts by binding to the P2 promoter ; only one other direct target of MBP-1, the COX2 gene, has been identified so far