Grünberg et al., Tumour Biol 2000
(Breast Neoplasms) :
In contrast, CAL51 cells were overall less sensitive to differentiation induction attempts ; only TNF-alpha stimulated MUC1, isoactin and epithelial cell adhesion molecule ( Ep-CAM ) expression
Gires et al., Cancer 2001
:
TNFalpha induced inhibition of the EpCAM expression is mediated by TNF receptor 1 through the TNF receptor associated death domain protein ( TRADD ) and by the activation of nuclear factor kappaB (NF-kappaB), and it can be blocked by dominant negative variants of TRADD and the NF-kappaB inhibitor, IkappaB