Gene interactions and pathways from curated databases and text-mining

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LY96 — NFKB1

Text-mined interactions from Literome

Gomi et al., J Immunol 2002 : ( R ) -Flavolipin, in which the configuration of the lipid moiety is R, induced NF-kappaB activation via the TLR4-MD-2 complex , but ( S ) -flavolipin did not
Muroi et al., Infect Immun 2002 : These results indicate that the polysaccharide portion covalently bound to lipid A plays the principal role in Salmonella LPS induced activation of NF-kappaB through human CD14/TLR4/MD-2
Ikeda et al., Immunopharmacol Immunotoxicol 2005 : NF-kappaB activation via TLR2, TLR1/ TLR2, TLR2/TLR6, and TLR4/MD-2/CD14 also was enhanced by stimulation with ZWS and ZWIS
Lotz et al., J Exp Med 2006 : Although the lipopolysaccharide (LPS) receptor complex TLR4/MD-2 was present in fetal, neonatal, and adult IECs, LPS induced nuclear factor kappaB (NF-kappaB) activation and chemokine ( macrophage inflammatory protein 2 [ MIP-2 ] ) secretion was only detected in fetal IECs