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CRP — NFKB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Innatedb Interaction: NFKB1 — CRP (unknown, -) Agrawal et al., J Immunol 2001*
• IRef Innatedb Interaction: NFKB1 — CRP (unknown, -) Choi et al., Nucleic Acids Res 2007*
• IRef Innatedb Interaction: NFKB1 — CRP (unknown, -) Cha-Molstad et al., Mol Immunol 2007*

Text-mined interactions from Literome

Ikeda et al., Cardiovasc Res 2002 (Cardiomyopathy, Dilated...) : Addition of IL-1beta activated NF-kappaB in cardiac myocytes, while CRP did not affect IL-1beta induced NF-kappaB activation
Wang et al., Clin Chim Acta 2005 : The CRP also significantly induces the activation of NF-kappaB in endothelial cells, and those effects were apparently inhibited by 10 micromol/l of fluvastatin, but not complete
Kawanami et al., Atherosclerosis 2006 (Atherosclerosis) : C-reactive protein induces VCAM-1 gene expression through NF-kappaB activation in vascular endothelial cells
Nakakuki et al., Arterioscler Thromb Vasc Biol 2005 (Atherosclerosis...) : NF-kappaB activity was markedly enhanced by CRP and pretreatment with Y-27632 inhibited its activation
Chang et al., Nephron. Experimental nephrology 2005 (Inflammation) : C-reactive protein induces NF-kappaB activation through intracellular calcium and ROS in human mesangial cells ... CRP increased NF-kappaB binding activity in a dose dependent manner ( 12.5-100 microg/ml ), which was induced within 1 h after incubation and peaked around 3 h. CRP also increased the MCP-1 mRNA expression via activation of NF-kappaB ... Calcium chelator, BAPTA-AM and anti-oxidants such as N-acetylcysteine and tiron suppressed CRP induced NF-kappaB activation
Lin et al., Biol Pharm Bull 2005 : Therefore, we studied the effects of CRP and lovastatin on NF-kappaB activation in human umbilical vein endothelial cells ( HUVECs )
Liuzzo et al., J Am Coll Cardiol 2007 (Angina, Unstable) : C-reactive protein induced a significant but modest in vitro NF-kappaB activation in human monocytes ( p = 0.002 )