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APOB — CRK

Text-mined interactions from Literome

Hackeng et al., Thromb Haemost 1999 : Inhibition of LDL binding by modification of apo B100 lysines reduced p38MAPK-activation by 80 %
Feng et al., Atherosclerosis 2001 : Activated p38 alpha is known to be involved in the stabilization of cyclooxygenase-2 mRNA in response to stimuli such as lipopolysaccharide ; however, in the setting of oxidized LDL induced p38 alpha activation, COX-2 mRNA levels were not affected
Dobreva et al., J Lipid Res 2003 (MAP Kinase Signaling System) : This activation did not require the recruitment of the LDL receptor (LDLR), because LDLs efficiently stimulated the p38 MAPK pathway in human and mouse fibroblasts lacking functional LDLR, and because receptor associated protein, an LDLR family antagonist, did not block the LDL induced p38 activation
Korporaal et al., J Biol Chem 2004 : Indeed, LDL was unable to induce p38MAPK activation in platelets of apoER2-deficient mice