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GCG — GPI
Text-mined interactions from Literome
Fenton et al., Respir Physiol 1978
(Hypercapnia) :
A similar degree of hypercapnia decreased the
pHi to only 6.95 in the presence of DBcAMP and to only 6.96 in the
presence of
glucagon
Ahrén et al., Peptides 1989
:
Since VIP and
PHI both
stimulate insulin and
glucagon secretion, we investigated the effects of helodermin on insulin and glucagon secretion in the mouse, both in the basal state and during administration of glucose and the cholinergic agonist carbachol
Ahrén et al., Neuropeptides 1988
:
It was found that
PHI did not
affect basal levels of insulin of
glucagon ... The
glucagon response to carbachol was
potentiated by
PHI ( 1.0 and 4.0 nmol/kg ) by approximately 40 % ( P less than 0.05 ) and 55 % ( P less than 0.01 ), respectively, whereas the terbutaline induced increase in plasma glucagon levels was not affected by PHI ... In summary,
PHI potentiates glucose induced insulin secretion and carbachol
induced glucagon secretion in the mouse
Szecówka et al., Am J Physiol 1983
:
PHI increased the release of insulin,
glucagon , and somatostatin ... In the absence of glucose,
PHI ( 1 nmol/liter )
stimulated glucagon release ... When arginine was used as a secretagogue,
PHI ( 10 nmol/liter )
potentiated secretion of insulin,
glucagon , and somatostatin
Guo et al., Zhonghua Yi Xue Za Zhi (Taipei) 1994
:
Present observations indicate that
glucagon and HNBB may
inhibit serum
PGI level, whereas the former has the additional effect of inhibiting serum gastrin level