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IL8 — PKD1

Text-mined interactions from Literome

Ivison et al., J Immunol 2007 : Third, pharmacologic inhibition of PKC or PKD with Gö6976 resulted in reduced expression and secretion of IL-8 and prevented the flagellin induced activation of p38 MAPK, but treatment with the PKC inhibitor Gö6983 had no significant effects on these phenotypes ... Finally, involvement of PKD in the p38 mediated IL-8 response to flagellin was confirmed by small hairpin RNA mediated gene silencing
Steiner et al., Cell Immunol 2010 : Flagellin stimulation of cells activated PKD1, and inhibition of PKD1 reduced flagellin induced interleukin-8 (IL-8) production in epithelial cells
Kempkes et al., J Invest Dermatol 2012 (Melanoma...) : Downregulation of PKD1 by siRNA resulted in diminished proliferation, decreased avß3 integrin regulation, and secretion of pro-angiogenic chemokine IL-8 in WM9 cells