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CCND1 — WNT11
Text-mined interactions from Literome
Hocevar et al., EMBO J 2003
:
Ectopic expression of Dab2 in NIH-3T3 mouse fibroblasts attenuates canonical
Wnt/beta-catenin mediated signaling, including accumulation of beta-catenin, activation of beta-catenin/T-cell-specific factor/lymphoid enhancer binding factor 1-dependent reporter constructs, and endogenous
cyclin D1 induction
Pradeep et al., Oncogene 2004
(Stomach Neoplasms) :
Since mature, amidated gastrin ( G-17 ) can induce cyclin D1, we determined whether G-17 mediated induction of
cyclin D1 transcription
involved Wnt signaling and CRE binding protein ( CREB ) pathways
Katoh et al., Cancer Biol Ther 2007
(Helicobacter Infections...) :
WNT-beta-catenin-TCF/LEF signaling
induces upregulation of MYC,
CCND1 , WISP1, FGF20, JAG1 and DKK1 genes ...
WNT-beta-catenin-TCF/LEF signaling
induces upregulation of MYC,
CCND1 , WISP1, FGF20, JAG1 and DKK1 genes
Lavergne et al., Oncogene 2011
(Colorectal Neoplasms...) :
One of such molecules is V3Nter, a soluble SFRP-like frizzled polypeptide that binds to Wnt3a and
inhibits Wnt signaling and expression of the ß-catenin target genes
cyclin D1 and c-myc. V3Nter is derived from the cell surface extracellular matrix component collagen XVIII
Marchand et al., Aging Cell 2011
:
In vitro,
Wnt treatment
induced proliferation and
cyclin D1 expression in VSMC from young ( 6 weeks old ) rats but not in cells from older rats ( 8 months old ), even though low-density lipoprotein receptor related protein 6 and ß-catenin phosphorylation, and ß-catenin nuclear translocation demonstrated ß-catenin activation in both cell types ... Beta-catenin silencing demonstrated that
Wnt induction of
cyclin D1 expression is ß-catenin dependent
Zhang et al., Hum Pathol 2012
(Carcinoma, Papillary...) :
In conclusion, we have demonstrated that expression of
cyclin D1 is linked to nodal metastases and that cyclin D1 levels are
regulated by
Wnt/ß-catenin signaling