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CRK — TAB1

Text-mined interactions from Literome

Ge et al., Science 2002 (MAP Kinase Signaling System) : We detected formation of a TRAF6-TAB1-p38alpha complex and showed stimulus-specific TAB1 dependent and TAB1 independent p38alpha activation
Edlund et al., Mol Biol Cell 2003 (Prostatic Neoplasms) : Ectopic expression of wild-type TAK1 promoted TGF-beta1 induced phosphorylation of p38 and apoptosis, whereas dominant negative TAK1 reduced TGF-beta1 induced phosphorylation of p38 and apoptosis ... Moreover, ectopically expressed Smad7 enhanced the coimmunoprecipitation of HA-MKK3 and Flag-p38, supporting the notion that Smad7 may act as a scaffolding protein and facilitate TAK1- and MKK3 mediated activation of p38
Cheung et al., Biochem J 2004 : The SAPK2a/p38alpha mediated phosphorylation of TAB2 and TAB3 may contribute to the SAPK2a/p38alpha mediated feedback control of TAK1 activity that also involves the phosphorylation of TAB1
Hammaker et al., J Immunol 2004 (Arthritis, Rheumatoid...) : Of interest, MEKK1 immunoprecipitates from IL-1 stimulated FLS appeared to activate c-Jun through the JNK pathway and TAK1 activation of c-Jun was dependent on JNK, ERK, and p38
Ohkusu-Tsukada et al., Mol Cell Biol 2004 (MAP Kinase Signaling System) : Regulation of the maintenance of peripheral T-cell anergy by TAB1 mediated p38 alpha activation
Lu et al., J Biol Chem 2006 (MAP Kinase Signaling System) : Although TAB-1 mediated p38 activation has been implicated in ischemic heart, the biological consequences and downstream signaling of TAB-1 mediated p38 activation in cardiomyocytes is largely unknown
Kang et al., J Biol Chem 2006 (MAP Kinase Signaling System) : In addition, our data suggest interference among different pathways because TAB1 had an inhibitory effect on p38alpha phosphorylation in the peroxynitrite induced approximately 85-kDa complex
Kim et al., American journal of physiology. Renal physiology 2007 : TGF-beta activated kinase 1 and TAK1 binding protein 1 cooperate to mediate TGF-beta1 induced MKK3-p38 MAPK activation and stimulation of type I collagen
Suzuki et al., J Biol Chem 2007 (Cell Transformation, Viral...) : In addition, ATF2, but not CREB, was a target for the TAK1-JNK pathway, and p38 negatively regulated TAK1 activity through TAB1 phosphorylation
Makeeva et al., Endocrinology 2008 : We conclude that TAB1alpha , but not TAB1beta, plays an important role in the activation of p38 in insulin producing cells and therefore also in cytokine induced beta-cell death
Shin et al., Biochim Biophys Acta 2009 : EGFR mediated phosphorylation of TAB1 was completely inhibited by a chemical inhibitor and siRNA of p38alpha
Tran et al., J Biol Chem 2012 (MAP Kinase Signaling System) : In agreement with this, overexpression of ASK1 or TAK1 resulted in enhanced p38MAPK activation, and their knockdown inhibited p38MAPK in C2C12 cells