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CDK2 — MCL1

Text-mined interactions from Literome

Scrace et al., Cell cycle (Georgetown, Tex.) 2008 : CDK inhibitors dramatically reduced levels of the anti-apoptotic proteins, Mcl-1 and XIAP, but siRNA mediated suppression of Mcl-1 and XIAP did not induce cell death in the osteosarcoma cells used in this study
Miller et al., PloS one 2013 (Breast Neoplasms) : A Cdk inhibitor, roscovitine, blocked paclitaxel induced MCL-1 degradation and apoptosis, suggesting that Cdk activation at mitotic arrest could induce subsequent MCL-1 degradation in a proteasome dependent manner