Falck et al., EMBO Rep 2012
:
Thus, CDK mediated NBS1 phosphorylation defines a molecular switch that controls the choice of repair mode for DSBs
Wohlbold et al., PLoS Genet 2012
:
In vivo, selective inhibition of Cdk2 delayed and diminished Nbs1-Ser432 phosphorylation during S phase, and mutation of Ser432 to Ala or Asp increased IR-sensitivity
Wang et al., PLoS Genet 2013
(Genomic Instability) :
Most notably, this CDK dependent CtIP and Nbs1 interaction facilitates ATM to phosphorylate CtIP in a substrate-specific manner