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IL12B — IL22

Text-mined interactions from Literome

Chen et al., Arthritis Rheum 2007 : However, IL-23 up-regulated its own receptor and was an important inducer of IL-17 and IL-22
Kreymborg et al., J Immunol 2007 (Encephalomyelitis, Autoimmune, Experimental) : We found that CNS invading encephalitogenic Th17 cells coexpress IL-22 and that IL-22 is specifically induced by IL-23 in autoimmune-pathogenic CD4+ T cells in a time- and dose dependent manner
Zheng et al., Nat Med 2008 (Enterobacteriaceae Infections) : We also find that IL-23 is required for the early induction of IL-22 during C. rodentium infection, and adaptive immunity is not essential for the protective role of IL-22 in this model
Schulz et al., J Immunol 2008 (Necrosis...) : Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23 dependent IL-22 , but not IL-17 ... In conclusion, IL-23 dependent IL-22 , but not IL-17 production is associated with protection against systemic infection with S. Enteritidis in the absence of IL-12
Siegemund et al., Int Immunol 2009 (Salmonella Infections) : The early IL-22 production was completely IL-23 dependent
Sutton et al., Immunity 2009 (Encephalomyelitis, Autoimmune, Experimental) : Here, we show that gammadelta T cells express IL-23R and the transcription factor RORgammat and produce IL-17, IL-21, and IL-22 in response to IL-1beta and IL-23 , without T cell receptor engagement
Rácz et al., Expert reviews in molecular medicine 2009 (Dermatitis...) : IL-23 stimulates the secretion of IL-22 by T helper 17 cells, and IL-22 induces epidermal hyperplasia
Mus et al., Arthritis Rheum 2010 (Arthritis, Experimental) : In contrast to TGFbeta1/IL-6, IL-23 was critical for the induction of IL-22 in CD4+ T cells from both naive and CII immunized DBA/1 mice
Cella et al., Proc Natl Acad Sci U S A 2010 : Natural killer-22 ( NK-22 ) cells are a human NK cell subset situated in mucosal associated lymphoid tissues that specialize in IL-22 secretion in response to IL-23 ... IL-1beta promoted constitutive IL-22 secretion rather than acute IL-22 production in response to IL-23 and induced IL-17 in some cells
Tang et al., Blood 2011 : IL-1ß and IL-23 stimulation results in significant IL-22 but not interferon-? production
Graham et al., PloS one 2011 (Coinfection...) : IL-22 production is regulated by IL-23 during Listeria monocytogenes infection but is not required for bacterial clearance or tissue protection ... Interestingly, IL-23 is required for the production of IL-22 during primary, but not secondary, LM infection
Zenewicz et al., Int Immunol 2011 (Communicable Diseases) : T ( h ) 22 cells produce IL-22 in response to IL-6 and tumor necrosis factor a (TNF-a), particularly in the skin, whereas ?d T cells produce IL-22 in response to IL-23 , particularly in the lung ... NK cells produce IL-22 in response to IL-12 and IL-18 or IL-23 ... NK cells produce IL-22 in response to IL-12 and IL-18 or IL-23
Ness-Schwickerath et al., Cell Mol Life Sci 2011 : In contrast, IL-17A and IL-22 production by murine ?d T cells is innately programmed during thymic ontogeny but requires IL-23 and IL-1ß for maintenance
Geremia et al., J Exp Med 2011 (Colitis, Ulcerative...) : IL-23-driven inflammation has been primarily linked to Th17 cells ; however, we have recently identified a novel population of innate lymphoid cells ( ILCs ) in mice that produces IL-17, IL-22 , and IFN-? in response to IL-23 and mediates innate colitis ... IL17A and IL17F expression is restricted to CD56? ILCs, whereas IL-23 induces IL22 and IL26 in the CD56? ILC compartment
Sarin et al., Proc Natl Acad Sci U S A 2011 (Inflammatory Bowel Diseases) : We find that CD4+CD45RO+ and CD8+ T cells from healthy R381Q IL23R carriers show decreased IL-23 dependent IL-17 and IL-22 production relative to WT IL23R individuals
Xu et al., Eur J Immunol 2011 (Hepatitis, Animal) : Finally, it was revealed that STAT3, STAT4 and Notch contributed to the production of both the cytokines, and that the AHR was important only for IL-22 production in response to Con A and IL-23 in liver mononuclear cells
Gessner et al., Infect Immun 2012 (Pulmonary Aspergillosis) : IL-22 production was additionally found to be independent of IL-1ß, IL-6, or IL-18 but required IL-23
Dudakov et al., Science 2012 : IL-22 , which signaled through thymic epithelial cells and promoted their proliferation and survival, was up-regulated by radio-resistant ROR? ( t ) ( + ) CCR6 ( + ) NKp46 ( - ) lymphoid tissue inducer cells after thymic injury in an IL-23 dependent manner
Awoniyi et al., PloS one 2012 (Salmonella Infections) : IL-12 and IL-23 regulate innate and adaptive immunity to microbial pathogens through influencing the expression of IFN-?, IL-17, and IL-22 ... IL-12 and IL-23 regulate innate and adaptive immunity to microbial pathogens through influencing the expression of IFN-?, IL-17, and IL-22
Basu et al., Immunity 2012 (Enterobacteriaceae Infections) : Whereas IL-22 production by ILCs was strictly IL-23 dependent , development of IL-22 producing CD4 ( + ) T cells occurred via an IL-6 dependent mechanism that was augmented by, but not dependent on, IL-23 and was dependent on both transcription factors T-bet and AhR
Behrends et al., PloS one 2013 (Tuberculosis) : Like IL-17A, IL-22 is expressed early after infection with Mtb in an IL-23 dependent manner
Zindl et al., Proc Natl Acad Sci U S A 2013 (Colitis) : Using a dextran sodium sulfate induced mouse model of acute colitis, we observed an IL-23 dependent up-regulation of IL-22 in the middle and distal colon at the onset of epithelial cell damage
Hegde et al., Cell Immunol 1995 (Neoplasms, Experimental) : AK-5 tumor induced expression of interleukin-12 : role of IL-12 in NK-mediated AK-5 regression