Huang et al., J Cell Biol 2000
:
Overexpression of ILK in the myoblasts inhibited the expression of myogenic proteins ( myogenin, MyoD, and myosin heavy chain ) and the subsequent formation of multinucleated myotubes
Wu et al., Am J Physiol Lung Cell Mol Physiol 2008
(Asthma) :
The depletion of ILK protein increased the expression of the smooth muscle differentiation marker genes myosin heavy chain ( SmMHC ), SM22alpha, and calponin and increased the expression of SmMHC protein ... Conversely, the overexpression of ILK protein reduced the mRNA levels of SmMHC, SM22alpha, and calponin and SmMHC protein