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SERPINA3 — TNF
Text-mined interactions from Literome
Kordula et al., J Neurosci 2000
(Alzheimer Disease) :
Mechanism of interleukin-1- and
tumor necrosis factor alpha dependent
regulation of the
alpha 1-antichymotrypsin gene in human astrocytes
Braghin et al., Neurosci Lett 2009
:
Alpha1-antichymotrypsin induces
TNF-alpha production and NF-kappaB activation in the murine N9 microglial cell line
Perlmutter et al., J Clin Invest 1986
(Carcinoma, Hepatocellular...) :
In picomolar concentrations,
TNF mediated reversible, dose- and time dependent increases in biosynthesis of complement proteins factor B and C3,
alpha 1 antichymotrypsin , and decreases in biosynthesis of albumin and transferrin in human hepatoma cell lines ( Hep G2, Hep 3B )
Magielska-Zero et al., Biochem Int 1988
(Carcinoma, Hepatocellular...) :
Human recombinant
tumor necrosis factor only slightly
affects production of
alpha 1-antichymotrypsin and albumin in a similar manner as leukocyte cytokines
Machein et al., Neuroreport 1995
(Astrocytoma) :
IL-1 beta and
TNF alpha , but not IL-6,
induce alpha 1-antichymotrypsin expression in the human astrocytoma cell line U373 MG ... We have studied the
effects of IL-1, IL-6 and
TNF alpha on the expression of the acute-phase protein
alpha 1-antichymotrypsin (ACT) in human astrocytoma cell lines
Lieb et al., J Neurochem 1996
(Astrocytoma) :
Interleukin-1 beta and
tumor necrosis factor-alpha induce expression of
alpha 1-antichymotrypsin in human astrocytoma cells by activation of nuclear factor-kappa B