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EDN2 — NOS1
Text-mined interactions from Literome
Barton et al., J Am Soc Nephrol 2000
(Glomerulosclerosis, Focal Segmental...) :
Dysfunctional renal
nitric oxide synthase as a determinant of salt-sensitive hypertension : mechanisms of renal artery endothelial dysfunction and
role of
endothelin for vascular hypertrophy and Glomerulosclerosis
Zhan et al., Sheng li ke xue jin zhan [Progress in physiology] 2000
(Cardiomyopathy, Hypertrophic) :
Angiotensin II ( AII ),
endothelin-1 (ET-1) and norepinephrine ( NE ) can
inhibit NOS activity and NO production, and induce hypertrophic response in cultured neonatal rat cardiomyocytes ; these effects of AII, ET-1 and NE are mediated respectively by AII receptor, ETA receptor and alpha 1-adrenergic receptor ; these effects of AII and ET-1 are mediated by PTX-sensitive G protein, while the effects of NE are mediated by PTX-insensitive G protein
Verma et al., J Surg Res 2004
(Anoxia) :
In some experiments, the effects of
endothelin ( ET ) receptor blockade ( with bosentan ) and
nitric oxide synthase (NOS) inhibition ( with L-NAME ) on pravastatin mediated cardioprotection were evaluated
Ohlstein et al., J Neurosurg 1992
:
An l-arginine analog inhibitor of
nitric oxide synthase , L-NG-monomethyl arginine ( L-NMMA, 200 microM ), did not significantly
affect basal immunoreactive
endothelin levels
Novella et al., Eur J Cardiothorac Surg 2007
(Cardiovascular Diseases) :
No change in the AVP response was produced by endothelium removal, exposure to the NO precursor ( 3 x 10 ( -4 ) M L-arginine ),
inhibition of
nitric oxide ( NO ) synthase ( 3 x 10 ( -5 ) M L-NAME ) or soluble guanylate cyclase ( 3 x 10 ( -6 ) M 1H- [ 1,2,4 ] oxadiazol [ 4,3,-alpha ] quinoxalin-1-one ( ODQ ) ), removal of the superoxide anion ( 100 U/ml superoxide dismutase ( SOD ) plus 1200 U/ml catalase ) or hydroxyl radical ( 10 ( -4 ) M deferoxamine ), or specific alpha1 - ( 10 ( -6 ) M prazosin ) or
endothelin ( 10 ( -5 ) M bosentan ) receptor antagonism
Franchi et al., Proc Natl Acad Sci U S A 1994
:
Cholinergic stimulation of vascular
endothelin activates
NO synthase (NOS) , leading to generation of NO from arginine
Lin et al., Eur J Endocrinol 1998
:
Role of
nitric oxide synthase in release of
endothelin from cultured human endometrial cells