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EP300 — PCNA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
PCNA
—
EP300
(physical association, affinity chromatography technology)
Hasan et al., Nature 2001*
-
IRef Biogrid Interaction:
PCNA
—
EP300
(direct interaction, pull down)
Hasan et al., Nature 2001*
-
IRef Biogrid Interaction:
PCNA
—
EP300
(direct interaction, pull down)
Hong et al., J Biol Chem 2003*
-
IRef Biogrid Interaction:
PCNA
—
EP300
(physical association, affinity chromatography technology)
Hong et al., J Biol Chem 2003*
-
IRef Biogrid Interaction:
PCNA
—
EP300
(physical association, affinity chromatography technology)
Cazzalini et al., Nucleic Acids Res 2008*
-
IRef Biogrid Interaction:
PCNA
—
EP300
(direct interaction, pull down)
Cazzalini et al., Nucleic Acids Res 2008*
-
IRef Biogrid Interaction:
PCNA
—
EP300
(physical association, affinity chromatography technology)
Naryzhny et al., J Biol Chem 2004*
-
MIPS CORUM ING1-p300-PCNA complex:
ING1-p300-PCNA complex complex (EP300-ING1-PCNA)
Vieyra et al., J Biol Chem 2002
-
IRef Corum Interaction:
Complex of ING1-PCNA-EP300
(association, anti bait coimmunoprecipitation)
Vieyra et al., J Biol Chem 2002
-
IRef Hprd Interaction:
PCNA
—
EP300
(in vitro)
Hasan et al., Nature 2001*
-
IRef Hprd Interaction:
PCNA
—
EP300
(in vivo)
Hasan et al., Nature 2001*
-
IRef Ophid Interaction:
PCNA
—
EP300
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Cazzalini et al., Nucleic Acids Res 2008
:
In vitro experiments show that inhibition of
p300 HAT activity
induced by
PCNA is relieved by p21, which disrupts the association between recombinant p300 and PCNA ... These results indicate that p21 is required during DNA repair to
regulate p300 HAT activity by disrupting its interaction with
PCNA
Sang et al., J Cell Physiol 1997
:
By interacting with key regulatory proteins such as the pRb family, cyclins,
cyclin dependent kinases and
p300/CBP of host cells, adenoviral E1A interferes with various cellular processes to provide a suitable environment for the replication of viruses