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IL6 — TRAF6

Text-mined interactions from Literome

Lomaga et al., Genes Dev 1999 (Osteopetrosis) : TRAF6 deficiency results in osteopetrosis and defective interleukin-1 , CD40, and LPS signaling
Mason et al., Infect Immun 2004 : TRAF6 dependent mitogen activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii
Ohishi et al., J Immunol 2005 (Bone Resorption) : In SOCS3-deficient BMMs, expression levels of TNF-receptor associated factor-6 and IkappaB were drastically reduced and receptor activator of the NF-kappaB ligand induced IkappaB phosphorylation was severely impaired in the presence of IL-6
Frobøse et al., Mol Endocrinol 2006 : Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex
Chang et al., J Biol Chem 2006 (Inflammation...) : An earlier study found that IL-17 activates NF-kappaB and MAPK pathways and requires TRAF6 to induce IL-6
Horie et al., Microbes Infect 2007 (HIV Infections) : TRAF activation of C/EBPbeta ( NF-IL6 ) via p38 MAPK induces HIV-1 gene expression in monocytes/macrophages
Chang et al., Cell Res 2007 (Inflammation) : IL-17A/F regulation of IL-6 and KC expression is dependent on IL-17RA and TRAF6