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CDK4 — PRDX2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 22 proteins (association, anti tag coimmunoprecipitation) Sablina et al., Cell 2007

Text-mined interactions from Literome

Sowa et al., Cancer Res 1999 : We previously reported that both sodium butyrate and trichostatin A (TSA) , both of which are known as inhibitors of histone deacetylase, arrest human tumor cells at G1 and G2-M and activate the cyclin dependent kinase inhibitor, the p21/WAF1/Cip1 gene promoter, through the Sp1 sites
Park et al., Int J Mol Med 2008 (Breast Neoplasms...) : In addition, TsA markedly down-regulated the expression of cyclin D1 and CDK4 , up-regulated the expression of p21WAF1 and p53 and induced cell cycle arrest at the G1 phase in MCF10A-ras cells