Gene interactions and pathways from curated databases and text-mining

◀ Back to IFNG

BAX — IFNG

Text-mined interactions from Literome

Marselli et al., J Clin Endocrinol Metab 2001 : IL-1beta, interferon gamma , and TNF alpha caused no major change in either islet cell survival or Bcl-2 and Bax mRNA expression after a 12-h incubation ; however, a marked increase in the amount of dead cells, with a major decrease of Bcl-2 mRNA expression, was observed after 72 h
Tesfaigzi et al., J Immunol 2002 (Eosinophilia...) : IFN-gamma caused Bax expression in IL-13 induced MCM in microdissected airway cultures ... Together, these data demonstrate that reduced IL-13 levels were sufficient to elicit maximum MCM, that IFN-gamma induces Bax in metaplastic mucus cells, and that Bax plays a critical role in the resolution of MCM, but not in the resolution of eosinophils
Liu et al., Cytokine 2003 : Effect of IFNgamma on caspase-3, Bcl-2 and Bax expression, and apoptosis in rabbit placenta
Xiang et al., Am J Respir Cell Mol Biol 2008 (Metaplasia) : These studies show that allergen induced MCM is a response to a combination of various cytokines at defined concentrations and that IFN-gamma requires Bax for the resolution of MCM
Guan et al., Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2009 : The results suggest that HeLa apoptosis was induced by tumor necrosis factor-a and interferon -gamma , and the increasing expression of P53 may induce the expression of Bax and prevent the expression of Bcl-2, via the mitochondrial induction of cell apoptosis