Martinez et al., Development 1999
:
These morphogenetic effects were apparently due to FGF8 mediated changes in gene expression in the vicinity of the bead, including a repressive effect on Otx2 and an inductive effect on En1 , Fgf8 and Wnt1 expression
Ohuchi et al., Dev Growth Differ 1999
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FGF10 can induce Fgf8 expression concomitantly with En1 and R-fng expression in chick limb ectoderm, independent of its dorsoventral specification
Deckelbaum et al., Development 2006
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Further analysis shows that EN1 regulates FGF signaling in calvarial osteoblasts
Shamim et al., Development 1999
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Using a retroviral vector to express En1 ectopically, we show that En1 can induce Fgf8 expression in midbrain and posterior diencephalon