Gene interactions and pathways from curated databases and text-mining

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CTNNB1 — PI3

Text-mined interactions from Literome

Hollande et al., J Biol Chem 2001 : Furthermore, glycine extended gastrin ( 17 ) induced a PI3-kinase mediated tyrosine phosphorylation of the adherens junction protein beta-catenin , partial dissociation of the complex between beta-catenin and the transmembrane protein E-cadherin, and delocalization of beta-catenin into the cytoplasm
Abbosh et al., Thyroid 2005 (Thyroid Neoplasms) : Activation of AKT by phosphatidylinositide-3 kinase (PI3K) , a RAS effector, results in GSK3beta phosphorylation and deactivation and subsequent beta-catenin upregulation in thyroid cancer
Vogelmann et al., J Cell Sci 2005 : The TGFbeta(1) induced beta-catenin phosphorylation was also dependent on PI3-kinase and Ras activity
Almeida et al., J Biol Chem 2005 : Wnt3a induced phosphorylation of GSK-3beta and downstream activation of beta-catenin mediated transcription required ERK, PI3K , and Akt signaling
Lee et al., Gastroenterology 2010 (Colitis...) : We investigated whether phosphoinositide 3-kinase (PI3K) is required for Akt mediated activation of beta-catenin during intestinal inflammation