Gene interactions and pathways from curated databases and text-mining

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CSNK2A1 — CTNNB1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: CTNNB1 → CSNK2A1 (decreases, CTNNB1 Activity) Fritz et al., Oncogene 1999*
    Evidence: Inhibition of CKII mediated phosphorylation of APE/Ref-1 blocked mutagen-stimulated increase in AP-1 binding. It also abrogated the induction of c-Jun protein and rendered cells more sensitive to induced DNA damage
  • KEGG Adherens junction: CSNK2A1/CSNK2A2/CSNK2B → CTNNB1 (protein-protein, activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *