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CCND1 — SHH
Text-mined interactions from Literome
Hartmann et al., Am J Pathol 2005
(Cerebellar Neoplasms...) :
In GCPs, a synergistic
effect of
Shh and Igf-II on proliferation and gli1 and
cyclin D1 mRNA expression was found
Vaillant et al., Development 2007
:
The binding of PN-1 to LRPs interferes with
SHH induced
cyclin D1 expression
Dormoy et al., Molecular cancer 2009
(Carcinoma, Renal Cell...) :
Gli1,
cyclin D1 , Pax2, Lim1, VEGF, and TGF-beta were exclusively expressed in tumors and were shown to be
regulated by
SHH , as evidenced by immunoblot after SHH inhibition
Li et al., Arterioscler Thromb Vasc Biol 2010
(Disease Models, Animal...) :
Inhibition of
Shh signaling in hVSMCs through treatment with cyclopamine or knockdown of Gli2 results in G ( 1 ) arrest and
reduced cyclin D1 , cyclin E, and phosphorylated retinoblastoma (pRB) levels