Gene interactions and pathways from curated databases and text-mining

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IL6 — ROR1

Text-mined interactions from Literome

Tanaka et al., J Immunol 2008 (Encephalomyelitis, Autoimmune, Experimental) : IL-6 plus TGF-beta enhanced retinoic acid receptor related orphan receptor ( ROR ) -gammat expression and suppressed IFN-gamma production in wild-type T cells, whereas these effects were severely impaired in SOCS1-deficient T cells
Li et al., PloS one 2010 (Leukemia, Lymphocytic, Chronic, B-Cell) : We transfected MM1 cells with truncated ROR1 promoter luciferase reporter constructs and found that IL-6 induced luciferase activity of ROR1-195 and upstream constructs
Chen et al., Cell Biochem Biophys 2012 (Encephalomyelitis, Autoimmune, Experimental) : We observed that overexpression of ROR?t in the presence of TGF-ß and IL-6 is highly efficient to produce Th17 cells