Gene interactions and pathways from curated databases and text-mining

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AKT1 — TLR3

Text-mined interactions from Literome

Miller et al., Arterioscler Thromb Vasc Biol 2005 (Atherosclerosis) : In turn, TLR4 regulated phosphorylation of ERK1/2 but not of Akt , suggesting that mmLDL induced PI3K activation is TLR4 independent
Santos-Sierra et al., EMBO J 2009 : In contrast to TLR2/6, TLR2/1 does not require Mal or MyD88 for Akt phosphorylation
Zhao et al., Mol Immunol 2010 : We also show that TLR3 induces interferon regulatory factor 3 (IRF3) activation by Akt via an mTOR-p70S6K-4EBP1 pathway
Nakamura et al., Rheumatol Int 2013 (Sjogren's Syndrome) : TLR3 mediated apoptosis and activation of phosphorylated Akt in the salivary gland epithelial cells of primary Sjögren 's syndrome patients