Gene interactions and pathways from curated databases and text-mining

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TP53 — WNK1

Text-mined interactions from Literome

Gu et al., Blood 2002 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : In the presence of wild-type ( wt ) p53, MDM2 increased p65 promoter activity by reversing p53 mediated suppression of p65
Shetty et al., Mol Cell Biol 2005 (Breast Neoplasms) : Reduction in p53 expression also blocks p65 binding to the intronic region of the DR5 gene, indicating cooperation between p53 and p65 in DR5 expression