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RHOA — TMED7

Text-mined interactions from Literome

Medina et al., J Biol Chem 2000 : Thus, PKA is responsible for the TSH-induction of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA levels, RhoA activation , and down-regulation of p27 ( kip1 )
Assoian et al., Dev Cell 2004 : Nuclear p27kip1 is an established inhibitor of cyclin dependent kinase-2, and it now appears that cytoplasmic p27kip1 inhibits the activation of RhoA
Besson et al., Genes Dev 2004 : Finally, we found that p27 ( Kip1 ) binds to RhoA, thereby inhibiting RhoA activation by interfering with the interaction between RhoA and its activators, the guanine-nucleotide exchange factors ( GEFs )
Moss et al., J Biol Chem 2010 : Silencing of p27 ( Kip1 ) with small interfering RNA blocked the effects of rapamycin on migration and tube formation as well as RhoA activation and cytoskeletal reorganization
Weber et al., J Biol Chem 1997 : Ras stimulated extracellular signal related kinase 1 and RhoA activities coordinate platelet derived growth factor induced G1 progression through the independent regulation of cyclin D1 and p27 ... Overexpression of dominant negative forms of Ras or RhoA completely blocked PDGF induced p27 ( KIP1 ) degradation, but only dominant negative Ras inhibited cyclin D1 protein expression