Gene interactions and pathways from curated databases and text-mining

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COP — IL4

Text-mined interactions from Literome

Teitelbaum et al., Proc Natl Acad Sci U S A 1999 (Encephalomyelitis, Autoimmune, Experimental) : These T cell lines secrete the anti-inflammatory cytokines IL-10 and transforming growth factor type beta, but not IL-4 , in response to both Cop 1 and MBP
Aharoni et al., Proc Natl Acad Sci U S A 2000 (Encephalomyelitis, Autoimmune, Experimental) : Highly reactive Cop 1-specific T cell lines that secrete IL-4 , IL-5, IL-6, IL-10, and transforming growth factor-beta in response to Cop 1 and crossreact with myelin basic protein (MBP) at the level of Th2 cytokine secretion were established from both brains and spinal cords of Cop 1-treated mice
Farina et al., Brain 2001 (Multiple Sclerosis) : Treatment of multiple sclerosis with Copaxone (COP) : Elispot assay detects COP induced interleukin-4 and interferon-gamma response in blood cells