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COP — IL4
Text-mined interactions from Literome
Teitelbaum et al., Proc Natl Acad Sci U S A 1999
(Encephalomyelitis, Autoimmune, Experimental) :
These T cell lines secrete the anti-inflammatory cytokines IL-10 and transforming growth factor type beta, but not
IL-4 , in
response to both
Cop 1 and MBP
Aharoni et al., Proc Natl Acad Sci U S A 2000
(Encephalomyelitis, Autoimmune, Experimental) :
Highly reactive Cop 1-specific T cell lines that secrete
IL-4 , IL-5, IL-6, IL-10, and transforming growth factor-beta in
response to
Cop 1 and crossreact with myelin basic protein (MBP) at the level of Th2 cytokine secretion were established from both brains and spinal cords of Cop 1-treated mice
Farina et al., Brain 2001
(Multiple Sclerosis) :
Treatment of multiple sclerosis with Copaxone (COP) : Elispot assay detects
COP induced
interleukin-4 and interferon-gamma response in blood cells