Gene interactions and pathways from curated databases and text-mining

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IGFBP3 — PRG3

Text-mined interactions from Literome

De Ceuninck et al., Arthritis Res Ther 2004 (Osteoarthritis) : It antagonized the inhibitory effect of IGFBP-3 on IGF-1 dependent proteoglycan synthesis by rabbit chondrocytes
Chevalier et al., Br J Rheumatol 1996 (Osteoarthritis) : This study demonstrates that the ability of IGF-I to enhance proteoglycan synthesis varied among the OA samples and may in part be dependent on the local level of IGFBP-3
Morales et al., Arch Biochem Biophys 1997 : These results suggest that an overall effect of the endogenous IGF-BP activity in articular cartilage under the test conditions is the inhibition of IGF-1 stimulated proteoglycan synthesis