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GSK3B — PAF1
Text-mined interactions from Literome
Maggirwar et al., J Neurochem 1999
:
As the activation of platelet activating factor (PAF) receptors is critical for the induction of neuronal death by several candidate HIV-1 neurotoxins, we determined whether
PAF can also
activate GSK-3beta
Tong et al., Eur J Neurosci 2001
:
Therefore, we investigated the biological effects following
activation of
GSK-3beta by
PAF , and whether these effects were dependent on the culture conditions of the CGNs ... We show here that
activation of neuronal
GSK-3beta by
PAF is receptor-specific, with similar kinetics of activation in both monolayer cultures of CGNs that have ceased to migrate and reaggregate cultures of CGNs that are actively migrating
Nandy et al., J Cell Mol Med 2010
(Diabetes Mellitus, Type 2) :
Additionally,
PAF induced
GSK-3beta phosphorylation was linked to Rac-1 activation and Rho-A inactivation leading to migration