Gene interactions and pathways from curated databases and text-mining

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GNAQ — SLC2A4

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: SLC2A4 → GNAQ (increases, GNAQ Activity, SLC2A4 Activity) Lawrence et al., Mol Cell Biol 2001*
    Evidence: However, the same ARF6 inhibitory mutant blocked the stimulation of hexose uptake and GLUT4 translocation in response to either endothelin 1 or an activated form of Galphaq, Galphaq(Q209L). These results suggest that endothelin stimulates glucose transport through a pathway that is distinct from that utilized by insulin but is likely to depend on both a heterotrimeric G protein from the Gq family and the small G protein ARF6. These data are consistent with the interpretation that endothelin and ...