Gene interactions and pathways from curated databases and text-mining

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DST — ESR2

Text-mined interactions from Literome

Khurana et al., Endocrinology 2000 (Hyperprolactinemia) : BPA , OP, and, to a lesser extent, DES increased the expression of both ERalpha and ERbeta in the anterior pituitary of males, but not females, whereas the hypothalamic ERs were less responsive to these compounds
Matthews et al., Chem Res Toxicol 2001 (Breast Neoplasms) : These results demonstrate that BPA competes more effectively for binding to ERbeta, but induces ERalpha- and ERbeta mediated gene expression with comparable efficacy
Hess-Wilson et al., Environ Health Perspect 2007 (Adenocarcinoma...) : BPA dramatically attenuated estrogen receptor beta (ERbeta) expression ; this finding was specific to prostate tumor cells in which BPA induces cellular proliferation