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DST — ESR2
Text-mined interactions from Literome
Khurana et al., Endocrinology 2000
(Hyperprolactinemia) :
BPA , OP, and, to a lesser extent, DES
increased the expression of both ERalpha and
ERbeta in the anterior pituitary of males, but not females, whereas the hypothalamic ERs were less responsive to these compounds
Matthews et al., Chem Res Toxicol 2001
(Breast Neoplasms) :
These results demonstrate that
BPA competes more effectively for binding to ERbeta, but
induces ERalpha- and
ERbeta mediated gene expression with comparable efficacy
Hess-Wilson et al., Environ Health Perspect 2007
(Adenocarcinoma...) :
BPA dramatically
attenuated estrogen receptor beta (ERbeta) expression ; this finding was specific to prostate tumor cells in which BPA induces cellular proliferation