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IRF6 — MAP3K7

Text-mined interactions from Literome

Xiong et al., J Biol Chem 2011 : We report that endotoxin tolerization of THP1 cells and human monocytes impairs LPS mediated receptor recruitment and activation of IRAK4, ablates K63 linked polyubiquitination of IRAK1 and TRAF6, compromises assembly of IRAK1-TRAF6 and IRAK1-IKK? platforms, and inhibits TAK1 activation
Yao et al., Int Immunopharmacol 2013 (Inflammation...) : In addition, taraxerol significantly inhibited the formation of TAK1/TAK binding protein1 (TAB1), which was accompanied by inducing degradation of TAK1, decreasing LPS induced polyubiquitination of TAK1 as well as TAK1 phosphorylation
Menden et al., Am J Physiol Lung Cell Mol Physiol 2013 : TAK1 inhibition decreased LPS induced ICAM-1 expression in HPMEC, and Nox2 silencing attenuated LPS mediated TAK1 phosphorylation ( Thr184/187 )