Yoza et al., Cytokine 2011
(Sepsis) :
We further show TLR dependent NF?B p65 and histone H3 serine 10 phosphorylation binding at the promoter
Wu et al., Cell Physiol Biochem 2012
:
Ketamine ( 100 and 1000 µM ) reduced the expression of GFAP and the production of these proinflammatory cytokines, inhibited the expression of TLR4 and attenuated the phosphorylation of NF-?B p65 in astrocytes challenged by LPS