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EPHB2 — SNAP25
Text-mined interactions from Literome
He et al., American journal of physiology. Renal physiology 2003
:
SNP or
SNAP had no significant effect on cellular levels of cGMP, cAMP, cytosolic calcium, or phosphorylation of
ERK1 and ERK2
Xu et al., Am J Physiol Heart Circ Physiol 2004
(Heart Diseases...) :
A Western blotting study showed that
SNAP significantly
enhanced phosphorylation of
ERK , which was reversed by MPG
Jones et al., Biochem Biophys Res Commun 2004
:
SNAP , at 0.5-4 mM, significantly and dose-dependently
inhibited angiogenesis, PKC activity, and
ERK and c-Jun phosphorylation up to 80 %, 83 %, and 63 % and 73 %, respectively
Palen et al., Cardiovasc Res 2005
:
The basal interaction between
ERK1/2 and SHP-1 was decreased in
response to
SNAP stimulation
Magalhães et al., Int J Dev Neurosci 2006
:
Using purified cultures of glial cells we showed that the NO donor
SNAP produced an inhibition of 50 % in cell proliferation and did
stimulate ERK1/2 phosphorylation, indicating that the inhibition of this pathway was not involved in its cytostatic effect
Li et al., Apoptosis 2006
(Myocardial Reperfusion Injury) :
However, treatment with U0126 completely blocked
SNAP induced
ERK activation and markedly, although not completely, inhibited the cardioprotection exerted by SNAP
Arai et al., Biochem Biophys Res Commun 2006
:
Downstream to p21Ras, the MAP Kinases
ERK1/2 were
activated by
SNAP under conditions that promote TRX-1 nuclear translocation ... Inhibition of MEK prevented
SNAP stimulated
ERK1/2 activation and TRX-1 nuclear migration