Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Sanchez-Prieto et al., Oncogene 2002 (Bone Neoplasms...) : Furthermore, we found that activation of p38 is sufficient to enhance the stability of p73, and that the transcriptional activation of p73 by c-Abl requires the activity of p38
An et al., Chin Med J (Engl) 2005 (Melanoma) : The expression of phosphorylated JNK and p38 also increased after the treatment with NCTD, and inhibitors of c-Jun NH2-terminal kinase (JNK) and p38 ( SP600125 and SB203580, respectively ) had significant inhibitory effects on the upregulation of phosphorylated JNK and p38 expression
Tang et al., J Biol Chem 2005 : Here we report that K-Ras activated p38gamma , a p38 MAPK family member, by inducing its expression without increasing its phosphorylation and that depletion of induced p38gamma suppressed Ras transformation in rat intestinal epithelial cells
Seay et al., J Pharmacol Exp Ther 2005 : In contrast, p38 inhibition did not alter Smad function, as assessed by translocation or reporter gene expression, but selectively inhibited p38 activity
Kim et al., Biol Pharm Bull 2010 : ER stress induced the phosphorylation of p38MAPK ( mitogen activated protein kinase ), and the p38MPAK inhibitor, SB203580, inhibited the resulting cell death and autophagy
An et al., PloS one 2011 : Here we show that the LZAP binds p38 , alters p38 cellular localization, and inhibits basal and cytokine stimulated p38 activity
Scott et al., J Biol Chem 2011 (MAP Kinase Signaling System) : Activation of p38 was redox-sensitive as H(2)O ( 2 ) caused p38 phosphorylation, and ROS scavenging significantly reduced LPS induced phospho-p38 expression
Cai et al., Fish Shellfish Immunol 2011 (DNA Virus Infections...) : The tissue distribution patterns of Ec-p38a , p38b and p38ß were different, and Ec-p38ß was up-regulated most obviously in head kidney after Singapore grouper iridovirus ( SGIV ) infection
He et al., Proc Natl Acad Sci U S A 2013 (Disease Models, Animal...) : Inhibition of p38 restored adipocyte differentiation from Shp2 ( -/- ) ES cells, and p38 signaling is also suppressed in obese patients and obese animals