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SMG1 — UPF3A

Pathways - manually collected, often from reviews:

• Reactome Reaction: UPF3A → SMG1 (indirect_complex) Denning et al., J Biol Chem 2001, Le Hir et al., EMBO J 2001, Yamashita et al., Genes Dev 2001, Lykke-Andersen et al., Science 2001, Ishigaki et al., Cell 2001, Gehring et al., Mol Cell 2003, Ohnishi et al., Mol Cell 2003, Palacios et al., Nature 2004, Shibuya et al., Nature structural & molecular biology 2004, Hosoda et al., Nature structural & molecular biology 2005, Gehring et al., Mol Cell 2005, Kashima et al., Genes Dev 2006, Kunz et al., RNA 2006, Chang et al., Annu Rev Biochem 2007, Chan et al., EMBO J 2007, Singh et al., Mol Cell 2007, Chamieh et al., Nature structural & molecular biology 2008, Ivanov et al., EMBO J 2008, Isken et al., Cell 2008, Stalder et al., Trends Cell Biol 2008, Mühlemann et al., Biochim Biophys Acta 2008, Rebbapragada et al., Curr Opin Cell Biol 2009, Yamashita et al., Genes Dev 2009, Gehring et al., PLoS Biol 2009, Chan et al., Nature structural & molecular biology 2009, Clerici et al., EMBO J 2009, Nicholson et al., Cell Mol Life Sci 2010, Maquat et al., Biochem Soc Trans 2009, Buchwald et al., Proc Natl Acad Sci U S A 2010, Hwang et al., Mol Cell 2010, Fernández et al., Nucleic Acids Res 2011, Chakrabarti et al., Mol Cell 2011
• Reactome Reaction: UPF3A → SMG1 (reaction) Denning et al., J Biol Chem 2001, Le Hir et al., EMBO J 2001, Yamashita et al., Genes Dev 2001, Lykke-Andersen et al., Science 2001, Ishigaki et al., Cell 2001, Gehring et al., Mol Cell 2003, Ohnishi et al., Mol Cell 2003, Palacios et al., Nature 2004, Shibuya et al., Nature structural & molecular biology 2004, Hosoda et al., Nature structural & molecular biology 2005, Gehring et al., Mol Cell 2005, Kashima et al., Genes Dev 2006, Kunz et al., RNA 2006, Chang et al., Annu Rev Biochem 2007, Chan et al., EMBO J 2007, Singh et al., Mol Cell 2007, Chamieh et al., Nature structural & molecular biology 2008, Ivanov et al., EMBO J 2008, Isken et al., Cell 2008, Stalder et al., Trends Cell Biol 2008, Mühlemann et al., Biochim Biophys Acta 2008, Rebbapragada et al., Curr Opin Cell Biol 2009, Yamashita et al., Genes Dev 2009, Gehring et al., PLoS Biol 2009, Chan et al., Nature structural & molecular biology 2009, Clerici et al., EMBO J 2009, Nicholson et al., Cell Mol Life Sci 2010, Maquat et al., Biochem Soc Trans 2009, Buchwald et al., Proc Natl Acad Sci U S A 2010, Hwang et al., Mol Cell 2010, Fernández et al., Nucleic Acids Res 2011, Chakrabarti et al., Mol Cell 2011

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: UPF3A — SMG1 (physical association, affinity chromatography technology) Kashima et al., Genes Dev 2006
• IRef Biogrid Interaction: UPF3A — SMG1 (physical association, affinity chromatography technology) Yamashita et al., Genes Dev 2001
• IRef Hprd Interaction: UPF3A — SMG1 (in vivo) Yamashita et al., Genes Dev 2001
• IRef Intact Interaction: Complex of SMG1-UPF2-UPF1-UPF3A (association, anti bait coimmunoprecipitation) Ivanov et al., EMBO J 2008
• IRef Intact Interaction: Complex of UPF3A-SMG1-SMG7-RBM8A-MAGOH (association, anti tag coimmunoprecipitation) Kashima et al., Genes Dev 2006

Text-mined interactions from Literome

Chiu et al., RNA 2003 : Upf1 phosphorylation is mediated by Smg1 , a phosphoinositol 3-kinase related protein kinase
Okada-Katsuhata et al., Nucleic Acids Res 2012 : Thus, the SMG-1 mediated phosphorylation of Upf1 creates a binding platforms for the SMG-5 : SMG-7 complex and for SMG-6, and triggers sequential remodeling of the mRNA surveillance complex for NMD induction and recycling of the ribosome, release factors and NMD factors