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NOX3 — RHO

Text-mined interactions from Literome

Gorzalczany et al., J Biol Chem 2000 : Amphiphile and p47(phox) independent NADPH oxidase activation by prenylated Rac1 is inhibited by Rho GDP dissociation inhibitor and by phosphatidylcholine vesicles, both competing with membrane for prenylated Rac1
Grizot et al., Biochemistry 2001 : The NADPH oxidase of phagocytic cells is regulated by the cytosolic factors p47(phox), p67(phox), and p40(phox) as well as by the Rac1-Rho-GDI heterodimer
Endres et al., Stroke 2004 (Substance Withdrawal Syndrome) : Rho negatively regulates endothelial nitric oxide synthase and Rac contributes to NAD ( P ) H-oxidase activation and superoxide production
Satoh et al., Proc Natl Acad Sci U S A 2006 (Cardiomegaly) : The Rho GTPase, Rac, regulates NADPH oxidase activity through interaction with gp91(phox) and p67(phox) ( in which `` phox '' is phagocyte oxidase )
Schlüter et al., Cardiovasc Res 2008 (Disease Models, Animal...) : Apocynin induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition
Kiyomoto et al., J Pharmacol Sci 2008 (Kidney Diseases) : In these renal cells, aldosterone induces cellular injury through NADPH oxidase dependent ROS production and activation of MAPKs or Rho-kinase
Borer et al., J Vet Pharmacol Ther 2013 : Fasudil ( 10 ( -6 ) to 10 ( -5 ) m ), a Rho kinase inhibitor, and apocynin ( 10 ( -3 ) to 3 x 10 ( -3 ) m ), an NADPH oxidase inhibitor , significantly ( P = 0.05 ) inhibited hypoxia enhanced contraction in response to PHE and 5-HT