Gene interactions and pathways from curated databases and text-mining

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IL12B — PRL

Text-mined interactions from Literome

Majumder et al., Int J Cancer 2002 (Carcinoma, Ehrlich Tumor...) : PRL induced release of IL-12 from EMs also, which suggested that the hormone might drive the TH1 response through IL-12
Yang et al., Int Immunopharmacol 2006 : In addition, PRL increased the expressions of IL-6, IL-10, IL-12 and TNF-alpha in SDCs
Tripathi et al., Int Immunol 2008 : AG490, inhibitor of JAK2, down-regulated transcription factors c-jun and STAT1 and inhibited the PRL induced IFN-gamma, TNF-alpha, IL-1 beta and IL-12p40 production in macrophages
Matsuse et al., Allergy & rhinology (Providence, R.I.) 2012 : The Prl did not significantly inhibit LPS induced IL-10 and IL-12 production in AS mice ... More importantly, Prl significantly increased IL-10 and IL-12 in AS mice after RSV infection