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LCN2 — TNF

Text-mined interactions from Literome

Cowland et al., J Immunol 2003 : IL-1beta induces a > 10-fold up-regulation of NGAL expression in the type II pneumocyte derived cell line A549 cells, whereas TNF-alpha , IL-6, and LPS had no effect ... TNF-alpha activation of NF-kappaB, in contrast, did not increase NGAL synthesis, even though induced binding of NF-kappaB to the NGAL promoter was observed in vitro
Cowland et al., J Immunol 2006 : Expression of NGAL is up-regulated in the lung epithelial cell line A549 by IL-1beta, but not by TNF-alpha , despite an induction of NF-kappaB binding to the NGAL promoter by both cytokines
Law et al., Diabetes 2010 (Insulin Resistance...) : On the other hand, the expression and activity of 12-lipoxygenase, an enzyme responsible for metabolizing arachidonic acid, and the production of tumor necrosis factor-alpha (TNF-alpha) , a critical insulin resistance inducing factor, are largely inhibited by lipocalin-2 deficiency ... Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate ( CDC ), an arachidonate lipoxygenase inhibitor, prevents TNF-alpha expression induced by lipocalin-2
Arena et al., Mediators Inflamm 2010 (Kidney Failure, Chronic) : Both IL-1ß and TNF-a regulate NGAL expression in polymorphonuclear granulocytes of chronic hemodialysis patients
Tadesse et al., Reprod Sci 2011 (Chorioamnionitis...) : IL-1ß, TNF-a , and LPS stimulated NGAL in cytotrophoblast cells ( not syncytiotrophoblast and decidua ) in vitro