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CDC42 — FYN

Pathways - manually collected, often from reviews:

• NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2: CDC42/GDP complex (CDC42) → VEGFR2 (dimer)/VEGFA (dimer)/Fyn/NCK1-2/PAK2 complex (KDR-VEGFA-FYN-NCK2_NCK1-PAK2) (modification, collaborate)
  Lamalice et al., Oncogene 2004, Lamalice et al., J Biol Chem 2006
  Evidence: mutant phenotype
• Reactome Reaction: FYN → CDC42 (indirect_complex) Gatti et al., J Biol Chem 1999, Chong et al., J Biol Chem 2001, Shekarabi et al., Mol Cell Neurosci 2002, Renkema et al., Mol Cell Biol 2002, Gerhardt et al., J Cell Biol 2003, Shekarabi et al., J Neurosci 2005, Lamalice et al., J Biol Chem 2006
• Reactome Reaction: FYN → CDC42 (reaction) Gatti et al., J Biol Chem 1999, Chong et al., J Biol Chem 2001, Shekarabi et al., Mol Cell Neurosci 2002, Renkema et al., Mol Cell Biol 2002, Gerhardt et al., J Cell Biol 2003, Shekarabi et al., J Neurosci 2005, Lamalice et al., J Biol Chem 2006, Han et al., Mol Cell Biol 1997*

Text-mined interactions from Literome

Khmelinskii et al., J Cell Biol 2007 : Cdc14 also controls the separase-Slk19 complex indirectly via the Aurora B kinase
Hoshina et al., Genes Cells 2007 : These results suggest that FAK/Fyn mediated activation of Rac1 and Cdc42 is critical for laminin induced outgrowth of oligodendrocyte processes