Gene interactions and pathways from curated databases and text-mining

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MMP3 — NOV

Text-mined interactions from Literome

Laurent et al., FASEB J 2003 (Brain Neoplasms...) : NOVH increases MMP3 expression and cell migration in glioblastoma cells via a PDGFR-alpha dependent mechanism
Kular et al., Journal of neuroinflammation 2012 (Disease Models, Animal...) : In vitro, results based on cultured DRG neurons showed that siRNA mediated inhibition of NOV enhanced IL-1ß- and TNF-a induced MMP-2, MMP-9 and CCL2 expression whereas NOV addition inhibited TNF-a induced MMP-9 expression through ß1 integrin engagement