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CCNB1 — CCND1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• MIPS CORUM Cell cycle kinase complex CDC2: Cell cycle kinase complex CDC2 complex (CCNB1-CCNB2-CCND1-CDK1-CDKN1A-PCNA) Zhang et al., Mol Biol Cell 1993
• IRef Corum Interaction: Complex of CCNB2-CDKN1A-CCNB1-PCNA-CDK1-CCND1 (association, anti bait coimmunoprecipitation) Zhang et al., Mol Biol Cell 1993
• IRef Intact Interaction: Complex of 30 proteins (association, tandem affinity purification) Varjosalo et al., Nat Methods 2013

Text-mined interactions from Literome

Cheng et al., Cancer Sci 2004 (Carcinoma, Hepatocellular...) : Etodolac induced p21WAF1/Cip1 and p27Kip1 expression and inhibited CDK2, CDK4, CDC2, cyclin A and cyclin B1 expression, but did not affect cyclin D1 or cyclin E. HGF and 10 % FBS induced ERK phosphorylation, but phosphorylation of p38, JNK and AKT was down-regulated by etodolac
Lavine et al., Mol Endocrinol 2008 : Analysis of cyclin and cdk mRNA and protein abundance revealed that CCK overexpression increased cyclin A, cyclin B , cyclin E, cdk1, and cdk2 with no change in cyclin D1 , cyclin D2, cyclin D3, cdk4, or cdk6 in mouse and human islets
Moro et al., Biochem Mol Biol Int 1997 : To our knowledge this is the first report showing positive effect of cyclin A, cyclin E and cyclin D1 on cyclin B1 activation and blocking of this activation by a Cdk2 dominant negative mutant